專利國別

  美國   

發表日期

2020-12-23 14:41:18

本校案號

P105020A

專利名稱

磁性金奈米聚集探針、其製造方法與使用其的生物粒子檢測方法「MAGNETIC NANOAGGREGATE-EMBEDDED BEAD, MANUFACTURING METHOD THEREOF AND BIOPARTICLE DETECTION METHOD USING THE SAME」

發明人

周禮君、顏詩穎

所屬院

理學院

提案單位

化學暨生物化學系所

類型

發明

專利權人

國立中正大學

申請號

15/648,102

申請日期

2017-07-12

公開號

0

公開日期

2018-07-19

證書號

US 10,722,534 B2

核准日期

2020-07-28

國際分類號

A61K-033/00(2006.01)；A61K-033/38(2006.01)；A61K-038/02(2006.01)；G01N-033/58(2006.01)；G01N-033/543(2006.01)；B82Y-005/00(2011.01)；A61K-047/52(2017.01)；A61K-047/69(2017.01)

專利權期間

2017.07.12~2037.07.12 （延長322天至2038.05.30）

專利摘要

A magnetic nanoaggregate-embedded bead (NAEB), a manufacturing method thereof and a bioparticle detection method using the same are disclosed. The magnetic NAEB has a protective nanoshell, noble metal nanoparticles, Raman reporter molecules and at least one magnetic nanoparticle. The protective nanoshell covers the noble metal nanoparticles, the Raman reporter molecules and the at least one magnetic nanoparticle. The noble metal nanoparticles, the Raman reporter molecules and the at least one magnetic nanoparticle form a magnetic nanoaggregate. Preferably, a chemical modification is performed on the magnetic NAEB, such that at least one targeting molecule is formed on an outer wall of the protective nanoshell, wherein a type of the targeting molecule is corresponding to a type of the bioparticle to be detected.

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