專利國別

  美國   

發表日期

2014-08-14 11:30:04

本校案號

P96005A

專利名稱

決定一細胞中的一個標的基因之生物功能「DETERMINATION OF THE BIOLOGICAL FUNCTION OF A TARGET GENE IN A CELL」

發明人

呂昱瑋、蕭淑惠、黃慧明

所屬院

理學院

提案單位

化學暨生物化學系所

類型

發明

專利權人

國立中正大學

申請號

12/135,540

申請日期

2008-06-09

公開號

US 2009-0305250 A1

公開日期

2009-12-10

證書號

US 8,067,163 B2

核准日期

2011-11-29

國際分類號

C12Q-001/68(2006.01)

專利權期間

2008.06.09~2028.06.09(延長226天至2029.01.21)

專利摘要

Disclosed herein is a method to determine the biological function(s) of a target gene in a cell, the steps of which involve separately culturing a first population and a second population of the cell under same culturing conditions, the first population of the cell differing from the second population of the cell in that the first population of the cell has accepted the introduction of a methylated polynucleotide; comparing the first population and the second population of the cell to determine which biological difference(s) is/are present therebetween; and determining which biological function(s) the target gene is associated with based on the determined biological difference(s) between the first population and the second population of the cell.

圖示