專利國別

  美國   

發表日期

2018-09-19 09:54:24

本校案號

P104022A

專利名稱

基於比色法之白蛋白檢測方法及其系統「METHOD FOR DETECTING ALBUMIN BASED ON COLORIMETRIC ASSAY AND SYSTEM THEREOF」

發明人

王少君、賴德勝、張廷州

所屬院

理學院

提案單位

化學暨生物化學系所

類型

發明

專利權人

國立中正大學

申請號

14/985,986

申請日期

2015-12-31

公開號

US 2017-0146507 A1

公開日期

2017-05-25

證書號

US 9,952,196 B2

核准日期

2018-04-24

國際分類號

B01L-003/00(2006.01)；B01D-061/44(2006.01)；B01D-061/46(2006.01)；G01N-001/40(2006.01)；G01N-021/25(2006.01)；G01N-027/447(2006.01)；G01N-033/68(2006.01)；G01N-033/487(2006.01)；G01N-021/552(2014.01)

專利權期間

2015.12.31~2035.12.31(延長342天至2036.12.07)

專利摘要

A method for detecting albumin based on a colorimetric assay and a system thereof are disclosed. Gold nanoparticles are added into the sample preparing device having a sample without spectroscopic tags, wherein the sample without spectroscopic tags is formed as the alkaline solution to avoid the interference substances adhering on the gold nanoparticles. The gold nanoparticles are concentrated by using the microfluidic concentrator with the circular ion exchange membrane by applying an external electric field across two electrodes. The image of the concentrated gold nanoparticles is captured by the image capturing device for measuring the saturation intensities of the image, wherein there is a relation between the saturation intensities and the concentration of the albumin in the sample without spectroscopic tags. The concentration of the albumin of the sample without spectroscopic tags is obtained by the relation and the measured saturation intensities.

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