【專利核准公告】P100044A-熱休克蛋白104啟動子置換之耐熱性酵母菌「RECOMBINANT THERMOTOLERANT YEAST WITH A SUBSTITUTE HEAT SHOCK PROTEIN 104 PROMOTER」
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專利國別 |
美國 |
發表日期 |
2014-08-14 10:00:26 |
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本校案號 |
P100044A |
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專利名稱 |
熱休克蛋白104啟動子置換之耐熱性酵母菌「RECOMBINANT THERMOTOLERANT YEAST WITH A SUBSTITUTE HEAT SHOCK PROTEIN 104 PROMOTER」 |
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發明人 |
黃光策、陳浩仁、李文乾、吳長育、陳信丞、吳瑜農、蔡夢栩、葉如萍、梁育維、賴昱璇 |
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所屬院 |
理學院 |
提案單位 |
系統生物學與組織工程研究中心 |
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類型 |
發明 |
專利權人 |
國立中正大學 |
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申請號 |
13/610,015 |
申請日期 |
2012-09-11 |
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公開號 |
0 |
公開日期 |
2011-02-10 |
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證書號 |
US 8,663,970 B1 |
核准日期 |
2014-03-04 |
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國際分類號 |
C12N-001/00(2006.01)；C12N-015/74(2006.01) |
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專利權期間 |
2012.09.11~2032.09.11 |
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專利摘要 |
The invention provides a yeast strain and a method for making the same. The method has the step of replacing the regulation region upstream of the hsp104 gene in the genome of the yeast, so as to accelerate and prolong the expression span of hsp104 gene and enhance the capability of the yeast to ferment and produce ethanol in a high-temperature environment. The yeast is capable of fermenting glucose at a temperature higher than 42.degree. C. to produce ethanol, or biomass ethanol, wherein the ethanol production ratio based on fermentation of glucose is higher than 97%. Being able to synchronize the degradation/hydrolysis stage and fermentation stage of biomass ethanol producing process, the yeast in accordance with the present invention is able to lower the production cost of biomass ethanol and further raise the productivity with its high ethanol production ratio. |
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圖示 |
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