【專利核准公告】P98013A-轉錄因子誘餌及應用「TRANSCRIPTION FACTOR DECOYS AND USE THEREOF」
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專利國別 |
美國 |
發表日期 |
2014-08-14 11:18:50 |
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本校案號 |
P98013A |
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專利名稱 |
轉錄因子誘餌及應用「TRANSCRIPTION FACTOR DECOYS AND USE THEREOF」 |
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發明人 |
黃光策、林見恩 |
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所屬院 |
工學院 |
提案單位 |
化學工程學系暨研究所 |
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類型 |
發明 |
專利權人 |
國立中正大學 |
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申請號 |
12/626,969 |
申請日期 |
2009-11-30 |
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公開號 |
US20110054010A1 |
公開日期 |
2011-03-03 |
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證書號 |
US 8,153,607 B2 |
核准日期 |
2012-04-10 |
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國際分類號 |
A61K-031/70(2006.01)；C07H-021/04(2006.01)；C12Q-001/00(2006.01) |
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專利權期間 |
2009.11.30~2029.11.30(延長16天至2029.12.16) |
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專利摘要 |
A pharmaceutical composition having a transcription factor decoy and a pharmaceutical acceptable carrier thereof is provided, wherein the transcription factor decoy is TCF decoy. A method for curing or preventing endotoxin-treated endothelial cells from apoptosis is provided. A method for treating or meliorating septic shock is also provided. The transcription factor decoy is effective on melioration of endothelial cell death after lipopolysaccharide challenge. Furthermore, the pharmaceutical composition is easy to be prepared, economic and has low immunogenicity. |
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圖示 |
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