【專利核准公告】P97004A-DIV-使用奈米聚集體顆粒的感測方法及其系統「DETECTION METHOD USING NANOAGGREGATE-EMBEDDED BEADS AND SYSTEM THEREOF」
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專利國別 |
美國 |
發表日期 |
2014-08-14 10:20:36 |
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本校案號 |
P97004A-DIV |
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專利名稱 |
使用奈米聚集體顆粒的感測方法及其系統「DETECTION METHOD USING NANOAGGREGATE-EMBEDDED BEADS AND SYSTEM THEREOF」 |
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發明人 |
周禮君、楊子萱、黃坪吉、林代宗 |
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所屬院 |
工學院 |
提案單位 |
化學工程學系暨研究所 |
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類型 |
發明 |
專利權人 |
國立中正大學 |
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申請號 |
13/134,417 |
申請日期 |
2011-06-07 |
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公開號 |
US 2011-0256578 A1 |
公開日期 |
2011-10-20 |
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證書號 |
US 8,187,820 B2 |
核准日期 |
2012-05-29 |
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國際分類號 |
G01N-033/53(2006.01) |
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專利權期間 |
2008.11.14~2028.11.14 |
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專利摘要 |
The invention discloses a detection method using nanoaggregate-embedded beads and system thereof, which are characterized in that the nanoaggregate of Raman dye and metal nanoparticles is coated by an inorganic oxide to form a nanoaggregate-embedded bead, and which is then conjugated with a probe molecule to form a sensor bead. The Raman spectra of the product formed by binding of the sensor bead and an analyte in a sample is detected for determining whether the analyte exists in the sample. In embodiment, the pH of the solution of metal nanoparticles is controlled to keep at 10, and the concentration of the Raman dye is controlled to keep between 1.times.10.sup.-6 M and 2.times.10.sup.-6 M for reducing the size of the nanoaggregate. |
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